Industry Insights
Lab Information Systems—Where the Needs are Greatest
December 15, 2025
Editor’s Note: This Industry Insights post was first published on November 22, 2022.
We at LigoLab have been looking forward to the next issue of CAP Today for quite some time, as it includes the publication’s LIS laboratory information system product guide, plus an informative roundtable discussion hosted by publisher Bob McGonnagle.
LigoLab CEO Suren Avunjian participated in the roundtable discussion and commented on what high-throughput COVID direct-to-consumer labs are doing as they pivot away from the pandemic and repurpose their PCR machines to run other molecular LIS tests. He also suggested that a growth area will continue to be direct-to-consumer lab testing and direct-to-organizational testing via consumer portals like LigoLab’s TestDirectly platform.
Discover More: Highlighting the Versatility of the TestDirectly Direct-to-Consumer Lab Testing Portal
He also addressed interoperability, or the lack thereof, within the industry and recommended LIS system software solutions that include an interface engine as the primary way to avoid using middleware for third-party and instrument interfaces.
Below is a link to the CAP Today discussion. After that, stay with us to examine widespread interoperability issues and how lab organizations can work with modern medical laboratory information system companies to overcome them.
CAP Today Link: Lab Information Systems - Where the Needs are Greatest
Why is Interoperability a Major Concern in Medical Labs?
Interoperability in medical laboratories is critical because it directly impacts efficiency, accuracy, compliance, and patient outcomes.
Clinical labs and pathology groups deal with vast amounts of data from multiple sources, including electronic health records (EHRs), hospital information systems (HIS), laboratory billing platforms, insurance providers, and regulatory agencies.
The inability to seamlessly exchange and integrate this data with healthcare LIS software can lead to operational bottlenecks, delayed test results, lab revenue cycle management (lab RCM) roadblocks, and even compromised patient care.
Key Challenges of Interoperability in Medical Labs
- Diverse Systems & Data Standards: Labs interact with numerous healthcare IT systems, each with separate protocols, formats, and standards (HL7, FHIR, LOINC, DICOM, etc.), making data exchange complex.
- Regulatory Compliance & Security: Labs must adhere to HIPAA, CLIA, and other regulations, ensuring secure data transmission while maintaining interoperability.
- Data Silos & Fragmentation: Many labs operate using legacy laboratory software systems that do not communicate effectively with modern EHRs, medical LIS, or lab revenue cycle management/laboratory billing solutions.
- Scalability & Integration with New Technologies: As healthcare evolves, labs must integrate with AI-driven diagnostics, molecular lab software testing, and at-home testing solutions, requiring advanced interoperability.
- Reimbursement & Lab Billing Challenges: Poor integration between medical LIS and lab RCM systems can lead to billing errors, denied claims, and revenue loss.
Discover More: Can Your Laboratory Information System Support the Latest LIS System Technology?
How Modern Laboratory Information System Vendors Address Interoperability Challenges
Modern laboratory information system vendors incorporate advanced LIS system technology to enhance interoperability and overcome these challenges. Here’s how:
- Standardized Data Exchange Protocols:
- Implementing HL7, FHIR, LOINC, and SNOMED CT to seamlessly facilitate communication between LIS systems, EHRs, and third-party platforms.
- Utilizing APIs and web services for real-time data sharing.
- Cloud-Based & Scalable Architecture:
- Enabling labs to integrate with multiple systems without heavy infrastructure investments.
- Supporting remote access and direct-to-consumer lab testing through online portals.
- Automated Lab Billing & Lab RCM Integration:
- Ensuring seamless capture of patient and insurance data to reduce lab billing errors and denials.
- Providing automated coding and claims management to optimize cash flow.
- AI & Machine Learning for Workflow Optimization:
- Predictive analytics to reduce errors and enhance test result accuracy.
- Decision-support tools for automated lab operations.
- Cybersecurity & Compliance Support:
- Ensuring secure, encrypted data transmission with built-in HIPAA-compliant frameworks.
- Providing audit trails and real-time monitoring for compliance reporting.
- Customizable & Modular LIS System Solutions:
- Allowing labs to scale functionalities based on needs, including molecular diagnostics, pathology, and outreach solutions.
- Integrating lab-specific workflows to enhance efficiency.
Industry Insights: The Competitive Edge in Laboratory Outreach - Enhancing Value Beyond Price
Next-Gen Medical LIS Systems: Empowering Labs with Automation, AI, and Cloud-Based Solutions
Interoperability remains a crucial concern in modern medical labs due to the complexity of healthcare IT ecosystems, but all is not lost.
Next-generation LIS software vendors can solve these challenges through robust integration frameworks, automation, cloud-based solutions, and AI-driven efficiency improvements.
By adopting advanced medical LIS and lab RCM solutions, labs can streamline operations, reduce costs, improve turnaround times, and deliver superior patient care.
Industry Insights: Examining the Pros and Cons of Cloud-Based LIS System Solutions
Enhancing Laboratory Efficiency with LigoLab’s All-in-One Medical LIS & Lab RCM Informatics Platform
Laboratory interfaces have long been known for their complexity and time-consuming nature. However, with LigoLab, that no longer has to be the case.
The all-in-one LigoLab Medical LIS & Lab RCM Informatics Platform is powered by a proprietary, built-in interface engine that ensures seamless interoperability across all laboratory departments.
This innovative LIS software solution eliminates manual data entry, reducing errors, saving staffing costs, and enabling labs to scale efficiently. By streamlining laboratory workflow management, LigoLab enhances productivity, expands service offerings, and ultimately increases revenue.
Unlike many legacy laboratory information system software applications, LigoLab provides a fully integrated, end-to-end LIS and RCM solution, eliminating data silos and redundant processes. This comprehensive approach ensures laboratories can operate at peak efficiency while maintaining total control over technical and financial operations.
Discover More: The Power of Integration - Unleashing the Potential of LigoLab's LIS System & Lab RCM Platform
Supporting All File Formats and Customization Levels
“If an electronic device can be interfaced, we can connect to it,” said Gor Kalantaryan, LigoLab’s Chief Operations Officer.
LigoLab’s interface engine supports multiple data exchange standards, including HL7, FHIR, XML, X12, CSV, PDF, Flat File, ASTM, and RESTful API. The system is backed by a team of experts who offer several levels of integration services:
- Full-Service Interface Management – LigoLab manages all integrations for its lab partner.
- IT Department Access – The client’s IT team manages interface development.
- Hybrid Model – The IT team handles the simple interfaces while LigoLab assists with the complex ones.
- Vendor-Managed Interfaces – LigoLab connects with external lab vendors that manage their own interface development
Overcoming Interoperability Challenges in Medical Labs
Many laboratories struggle with legacy LIS systems that cannot meet modern demands. Most off-the-shelf LIS lab solutions lack the customization and scalability needed for today’s dynamic laboratory environment.
LigoLab solves this issue with:
- Fully customizable medical LIS & lab RCM solutions tailored to each lab’s unique workflows.
- Dedicated interface support to assist with development, training, and ongoing optimization.
- A seamless integration process that reduces onboarding time and operational disruptions.
A Streamlined and Painless Interface Process
Many laboratories hesitate to implement new interfaces due to past challenges with their legacy LIS systems. However, LigoLab transforms this experience into a smooth and efficient process.
“When we first meet with clients, they often describe how painful past interface initiatives have been,” said Kalantaryan. “With LigoLab, these projects - which previously took months - can now be completed in days or even hours.”
A Customer-Centric Approach to LIS System Integration
Most LIS vendors create generic solutions that fail to address the specific needs of different laboratories, hospitals, and clinics. LigoLab takes a different approach by offering:
- Immediate support for customer requests through a dedicated team of interface professionals.
- Ongoing communication throughout the entire integration process.
- A proactive approach to interface optimization, ensuring smooth operations even after deployment.
Ensuring Long-Term Interface Stability
Unlike many laboratory information system companies that delay interface requests for support, LigoLab prioritizes interface health through proactive maintenance and real-time monitoring. By taking this approach, LigoLab prevents potential LIS system downtime and ensures constant interoperability.
Discover More: Stability and Performance - The Two Most Important Aspects of a Modern Laboratory Operation
LigoLab: Experts at Scaling Laboratory Operations
LigoLab’s advanced medical LIS & lab RCM informatics platform empowers laboratories to scale efficiently, improve turnaround times, and optimize revenue cycles.
By offering robust integration capabilities, customizable LIS system software, and unparalleled customer support, LigoLab enables their customers to transform their operations quickly and with minimal friction.
Ready to learn more about the LigoLab difference?
Contact a product specialist and set up an introductory call.
