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LigoLab’s Collection Model Combines Medical LIS & Lab RCM Workflows to Maximize Clean Claims and Laboratory Payments
December 17, 2025
Los Angeles, CA - Using patchwork laboratory software systems as separate applications to connect anatomic pathology, clinical laboratory, molecular diagnostics, laboratory billing/lab revenue cycle management (lab RCM), and direct-to-consumer lab testing workflows allows medical laboratories to get by, but at what cost?
These multiple-system diagnostic lab software arrangements are expensive, difficult to maintain, inefficient, and prone to data silos. They ultimately lead to laboratory billing issues as critical information is transferred from one system to another.
So what’s the best laboratory workflow management solution?
At LigoLab, the answer is clear. What’s needed most is a comprehensive clinical laboratory management system that supports and streamlines the life cycle of all operations, promotes business growth, and enables medical labs to retain customers and foster new business relationships.
Discover More: Why Integrated LIS System and Lab RCM Software is a Catalyst for Growth
LigoLab’s Medical LIS and Laboratory Billing Solutions Modernize and Automate Clinical Lab Workflow
LigoLab’s laboratory information system (LIS) software with embedded laboratory billing solutions removes the data silos and connects, merges, and integrates every lab process and department through an all-in-one informatics platform that serves as the focal point for all lab operations (administrative, technical, and financial). It modernizes by automating processes, streamlining clinical lab workflow, and eliminating human errors. Most importantly, it ensures data integrity and enables laboratories to embrace a new collection model.
Front-End Laboratory Billing Automation Means Much Less RCM Cycle Clean-Up
With LigoLab’s fully integrated medical LIS and laboratory billing platform, technical and financial workflows operate as one. This unified approach enables the laboratory billing process to start at order entry, rather than after final report sign-out, eliminating the downstream errors, rework, and denials that plague traditional, back-end billing models.
This front-end laboratory billing strategy is powered by advanced LigoLab platform capabilities, including real-time third-party integrations (that automatically code and validate claims before submission) and live payment queues that deliver complete operational visibility, ensuring no claim is overlooked and every case is actively managed to resolution.
These lab RCM capabilities deliver first-pass clean claim rates above 98% and drive revenue increases of 30% or more (adjusted for growth), without additional operating costs.
Learn more by reading our white paper (linked below) on the benefits of front-end laboratory billing.
Why Fragmented LIS Systems and Laboratory Billing Solutions Put Labs at Risk
As noted earlier, many medical laboratories continue to rely on standalone laboratory information system software and separate laboratory billing solutions, a fragmented approach that drives higher denial rates, costly write-offs, and limited visibility across the RCM cycle. As reimbursement pressure intensifies and margins tighten, pathology, clinical, and reference laboratories must reassess their LIS system and lab RCM strategies or face growing operational and financial strain.
This white paper examines the limitations of traditional laboratory revenue cycle management, presents a modern, integrated alternative, and outlines the advantages of a unified medical LIS and lab RCM platform. By merging technical and financial workflows, integrated LIS software improves efficiency, minimizes revenue leakage, and positions laboratories for long-term, sustainable growth.
White Paper: The Connected Laboratory - Leveraging Medical LIS & Lab RCM to Grow Your Business
The Benefits of LIS System and Lab RCM Integration
LigoLab’s laboratory revenue cycle management module stands out because it’s fully integrated within the unified LigoLab LIS software platform, eliminating the inefficiencies and revenue leakage common in standalone laboratory billing systems.
Here’s what makes LigoLab’s advanced LIS lab software special:
1. End-to-End Integration with the Laboratory Information System
Unlike traditional laboratory billing solutions that require middleware or manual reconciliation, LigoLab’s lab RCM is natively embedded within the LIS system. This ensures seamless data flow from order entry to final payment, eliminating discrepancies and delays.
2. Automated & Real-Time Laboratory Billing
- Instant Coding & Charge Capture: The lab revenue cycle management module automatically assigns CPT and ICD codes at order inception, ensuring accuracy.
- Automated Claim Scrubbing: Reduces denials by identifying errors before claims are sent to payers.
- Eligibility Verification & Prior Authorization: Built-in real-time insurance verification helps prevent rejections.
3. Reduced Denials & Faster RCM Cycle Reimbursements
By capturing clean data at the source, LigoLab significantly reduces denial rates and write-offs, leading to faster payments and improved cash flow.
4. Rule-Based Lab Billing Workflow & Customization
Labs can configure custom lab billing rules, payer-specific logic, and automated workflows, making the system adaptable to unique payer contracts, lab billing structures, and compliance requirements.
5. Advanced Lab RCM Analytics & Reporting
- Real-time dashboards provide full financial visibility.
- Customizable KPIs and trend analysis optimize lab billing performance.
- Data-driven insights enable proactive lab revenue cycle management solutions.
6. Lab Revenue Cycle Management Compliance & Security
LigoLab ensures compliance with HIPAA, Medicare, and payer guidelines, reducing risk while maintaining audit-ready documentation.
7. Scalable for Growth
Whether a small pathology lab or a large reference lab, LigoLab’s scalable architecture enables seamless expansion without any third-party laboratory billing applications.
Lab Billing Bottom Line
LigoLab’s unified medical LIS & lab RCM approach creates a frictionless revenue cycle, maximizing efficiency, accuracy, and profitability - a true game-changer in laboratory billing.
White Paper: Maximizing Your Lab’s Profitability - The Case for In-House Lab Billing
Protect Your Revenue
Learn how integrating LIS and lab billing applications reduces denials, improves visibility, and positions your lab for sustainable growth. Schedule a call with a LigoLab product specialist.
Act Now: Connect with a LigoLab Product Specialist Today!
Don’t Forget About LigoLab’s 99.9% Uptime Guarantee
LigoLab stands out in the LIS system and laboratory billing markets by offering an unmatched 99.9% uptime guarantee, ensuring laboratories experience minimal disruptions.
According to CEO Suren Avunjian, this commitment means labs can rely on LigoLab’s informatics platform to remain operational at all times, preventing workflow interruptions that could impact profitability.
Unlike other LIS laboratory information system companies, LigoLab guarantees uptime, demonstrating its confidence in the stability and resilience of its platform.
Built for Reliability, Scale, and Uninterrupted Laboratory Operations
Designed to support high-volume specimen processing and complex data management, the LigoLab platform delivers the scalability and resilience laboratories need to perform under heavy workloads. Advanced monitoring systems proactively identify and resolve potential issues before they impact operations, providing customers with confidence and peace of mind.
In the rare event of unplanned downtime, LigoLab offers service credits to affected customers, underscoring its commitment to laboratory success. As Avunjian notes, this uptime guarantee is supported by rigorous development, testing, and quality assurance processes, along with continuous investment in modern technology and infrastructure.
By prioritizing reliability, stability, and customer satisfaction, LigoLab delivers seamless, high-performance LIS software and laboratory billing solutions that minimize disruption while maximizing operational efficiency and profitability.
Industry Insights: Bridging the Gap in Modern Laboratories - Why a Comprehensive Digital Platform Outperforms a Basic Lab Information System
TestDirectly: Streamlined and Automated Direct-to-Consumer Lab Testing
Is your laboratory interested in joining a growing number of direct-to-consumer labs that are taking the next logical step to open a new revenue opportunity?
If yes, listen up. LigoLab has developed a dynamic direct-to-consumer lab testing portal called TestDirectly.
The TestDirectly direct-to-consumer lab testing portal connects patients and physicians with medical laboratories for efficient and effective personalized lab testing.
The portal supports all direct-to-consumer lab testing collection workflows (including at-home collections) while relieving labs from manual processes for order entry and case follow-up after sharing consumer lab reports with patients.
Learn more about the portal by clicking the link below.
Industry Insights: Consumerism and How Clinical Labs Can Take Advantage of a Growing Direct-to-Consumer Lab Testing Trend





